Category EV L15 The Dissolved Oxygen and Phototactic Response of Daphnia on

Pharmaceuticals

Abstract This experiment tested the aquatic organism, Daphnia magna, while on two

different pharmaceuticals, in two different phases. The pharmaceuticals

were lisinopril, an antihypertensive, and fluoxotine, an antidepressant.

Phase one tested the phototactic behavior of the daphnia and phase two

tested the dissolved oxygen.



Normally the daphnia are attracted to light, which is very important to them

as it where they find their food source. The hypothesis for phase one

states, “If pharmaceuticals commonly found in waste water effluents are

tested on Daphnia magna, then the pharmaceuticals adversely effects the

phototactic behavior of the daphnia.” The effect of pharmaceuticals on

Daphnia magna’s phototactic behavior was studied using a phototactic

light box. The daphnia were placed in test tubes containing five different

amounts of the pharmaceuticals, lisinopril and fluoxotine. The experiment

recorded the number of Daphnia magna swimming up and down a test

tube in a specific amount of time to observe the attraction to light. The total

response number of the daphnia’s attraction to light decreased as the

amount of pharmaceutical increased. The hypothesis was supported as

the daphnia’s phototactic behavior was adversely effected.



The hypothesis for phase two states, “If pharmaceuticals commonly found

in waste water effluents are tested on Daphnia magna, then the

pharmaceuticals raise the dissolved oxygen rate.” The dissolved oxygen

rate was tested using a portable dissolved oxygen meter and only one

amount of each pharmaceutical. The hypothesis was not supported

however, since there was little difference between the control, dissolved

oxygen of the daphnia on no pharmaceuticals, and the dissolved oxygen

of the daphnia on the pharmaceuticals. This was most likely because the

pharmaceuticals on daphnia only effects the behavior not the metabolism

of the daphnia.

Bibliography Cope, Gregory W., Shea Damian, Robert B. Bringolf, and Rebecca M.

Heltsley. Endocrine and Reproductive Effects of the Pharmaceutical

Fluoxetine on Native Freshwater Mussels. Rep. no. UNC-WRRI-382.

Department of Environmental and Molecular Toxicology, North Carolina

State University, Oct. 2007. Web.

<http://repository.lib.ncsu.edu/dr/bitstream/1840.4/4112/1/NC-WRRI-

382.pdf>.



"Effects of Alcohol and Nicotine on Daphnia." Washington Association of

Biomedical Research, Jan. 1998. Web.



Gale Parsons, Ivy. "The Effects of Fluoxetine on Agressive Behaviors in

Siamese Fighting Fish (Betta Splendens)."

Http://www.bettabrasil.com.br/downloads/the_effects_of_fluoxetine_on_

aggressive_behaviors_in_siamese_fighting_fish.pdf. Fall 2005. Web.



Marcus, Adam. "Happy Fish Go Hungry?: Scientific American."

Scientific American (2008). Science News, Articles and Information |
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